Dr Simoncelli’s research interests are on the application and development of nano-scale technologies to image, sense and manipulate biological objects. The lab uses a combination of experimental and computational techniques, including microscopy, optics, nano-fabrication, spatial statistics, and image processing. We are particularly interested in super-resolution fluorescence microscopy techniques, which are optical techniques that allow us to monitor the spatial organisation of single molecules and molecular assemblies. Our main biological application is in T cells, which are white blood cells that are essential for human immunity.