The Parsons lab is currently focused on using a range of live-cell advanced imaging approaches including FRAP, FRET and photo-activation to enable precise spatio-temporal dissection of receptor signalling. A key focus of has been in the development and implementation of novel imaging approaches and FRET-based biosensors to study cells within 2D and 3D environments. The team also has well-established collaborations with clinicians to study adhesion receptor signalling in skin blistering, cancer, wound healing and inflammation as well as multi-disciplinary projects with physicists and biophysicists to define spatio-temporal signalling events contributing to adhesion and migration in living cells. Maddy also has a strong working partnership with Nikon, which led to the establishment of the state-of-the-art, world-class Nikon Imaging Centre at King’s in 2012, and of which she is currently Director. Her group also currently work alongside other biotech and pharmaceutical companies to develop and apply advanced imaging approaches to basic mechanisms that underpin drug discovery.